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Protein phosphatase 2A regulates cytotoxicity and drug resistance by dephosphorylating AHR and MDR1
Protein phosphatase 2A (PP2A) is a serine/threonine dephosphorylating enzyme complex that plays numerous roles in biological processes, including cell growth and metabolism. However, its specific actions in many of these critical pathways are unclear. To explore mechanisms underlying metabolic enzym...
Autores principales: | Chen, Liping, Guo, Ping, Li, Wenxue, Jiang, Xinhang, Zhao, Qun, Li, Daochuan, Wang, Qing, Xiao, Yongmei, Xing, Xiumei, Pang, Yaqin, Aschner, Michael, Zhang, Lihua, Chen, Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118923/ https://www.ncbi.nlm.nih.gov/pubmed/35405096 http://dx.doi.org/10.1016/j.jbc.2022.101918 |
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