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RPS12 and UBC4 Are Related to Senescence Signal Production in the Ribosomal RNA Gene Cluster

Genome instability causes cellular senescence in many organisms. The rRNA gene cluster (rDNA) is one of the most unstable regions in the genome and this instability might convey a signal that induces senescence in the budding yeast. The instability of rDNA mostly depends on replication fork blocking...

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Detalles Bibliográficos
Autores principales: Yanagi, Shuichi, Iida, Tetsushi, Kobayashi, Takehiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119118/
https://www.ncbi.nlm.nih.gov/pubmed/35384721
http://dx.doi.org/10.1128/mcb.00028-22