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RPS12 and UBC4 Are Related to Senescence Signal Production in the Ribosomal RNA Gene Cluster
Genome instability causes cellular senescence in many organisms. The rRNA gene cluster (rDNA) is one of the most unstable regions in the genome and this instability might convey a signal that induces senescence in the budding yeast. The instability of rDNA mostly depends on replication fork blocking...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119118/ https://www.ncbi.nlm.nih.gov/pubmed/35384721 http://dx.doi.org/10.1128/mcb.00028-22 |