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Effects of TRAM-34 and minocycline on neuroinflammation caused by diabetic ketoacidosis in a rat model

INTRODUCTION: Diabetic ketoacidosis (DKA) causes acute and chronic neuroinflammation that may contribute to cognitive decline in patients with type 1 diabetes. We evaluated the effects of agents that reduce neuroinflammation (triarylmethane-34 (TRAM-34) and minocycline) during and after DKA in a rat...

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Detalles Bibliográficos
Autores principales: Glaser, Nicole, Chu, Steven, Weiner, Justin, Zdepski, Linnea, Wulff, Heike, Tancredi, Daniel, ODonnell, Martha E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119135/
https://www.ncbi.nlm.nih.gov/pubmed/35584854
http://dx.doi.org/10.1136/bmjdrc-2022-002777