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Studies in the antiviral molecular mechanisms of 25-hydroxycholesterol: Disturbing cholesterol homeostasis and post-translational modification of proteins

Efficient antiviral drug discovery has been a pressing issue of global public health concern since the outbreak of coronavirus disease 2019. In recent years, numerous in vitro and in vivo studies have shown that 25-hydroxycholesterol (25HC), a reactive oxysterol catalyzed by cholesterol-25-hydroxyla...

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Detalles Bibliográficos
Autores principales: Mao, Shijie, Ren, Jie, Xu, Ying, Lin, Jidong, Pan, Chuqiao, Meng, Yu, Xu, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119167/
https://www.ncbi.nlm.nih.gov/pubmed/35598845
http://dx.doi.org/10.1016/j.ejphar.2022.175033