Glycerol-3-Phosphate Dehydrogenase: The K120 and K204 Side Chains Define an Oxyanion Hole at the Enzyme Active Site

[Image: see text] The cationic K120 and K204 side chains lie close to the C-2 carbonyl group of substrate dihydroxyacetone phosphate (DHAP) at the active site of glycerol-3-phosphate dehydrogenase (GPDH), and the K120 side chain is also positioned to form a hydrogen bond to the C-1 hydroxyl of DHAP....

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Detalles Bibliográficos
Autores principales: Cristobal, Judith R., Richard, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119304/
https://www.ncbi.nlm.nih.gov/pubmed/35502876
http://dx.doi.org/10.1021/acs.biochem.2c00053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119304/
https://www.ncbi.nlm.nih.gov/pubmed/35502876
http://dx.doi.org/10.1021/acs.biochem.2c00053

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