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Initial TK-deficient HSV-1 infection in the lip alters contralateral lip challenge immune dynamics
Primary infection with herpes simplex type 1 (HSV-1) occurring around the mouth and nose switches rapidly to lifelong latent infection in sensitive trigeminal ganglia (TG) neurons. Sporadic reactivation of these latent reservoirs later in life is the cause of acute infections of the corneal epitheli...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119387/ https://www.ncbi.nlm.nih.gov/pubmed/35590057 http://dx.doi.org/10.1038/s41598-022-12597-4 |