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Ustilago maydis telomere protein Pot1 harbors an extra N-terminal OB fold and regulates homology-directed DNA repair factors in a dichotomous and context-dependent manner

The telomere G-strand binding protein Pot1 plays multifaceted roles in telomere maintenance and protection. We examined the structure and activities of Pot1 in Ustilago maydis, a fungal model that recapitulates key features of mammalian telomere regulation. Compared to the well-characterized primate...

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Detalles Bibliográficos
Autores principales: Zahid, Syed, Aloe, Sarah, Sutherland, Jeanette H., Holloman, William K., Lue, Neal F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119445/
https://www.ncbi.nlm.nih.gov/pubmed/35587917
http://dx.doi.org/10.1371/journal.pgen.1010182