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Ustilago maydis telomere protein Pot1 harbors an extra N-terminal OB fold and regulates homology-directed DNA repair factors in a dichotomous and context-dependent manner
The telomere G-strand binding protein Pot1 plays multifaceted roles in telomere maintenance and protection. We examined the structure and activities of Pot1 in Ustilago maydis, a fungal model that recapitulates key features of mammalian telomere regulation. Compared to the well-characterized primate...
Autores principales: | Zahid, Syed, Aloe, Sarah, Sutherland, Jeanette H., Holloman, William K., Lue, Neal F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119445/ https://www.ncbi.nlm.nih.gov/pubmed/35587917 http://dx.doi.org/10.1371/journal.pgen.1010182 |
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