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Characterization of proteolytic degradation products of vaginally administered bovine lactoferrin

When bovine lactoferrin (bLF) contacts human vaginal fluid (VF) it is subjected to proteolytic degradation. This report describes fragmentation patterns of bLF dosed vaginally in clinical trials or incubated ex vivo with VF. A consensus pattern of fragments was observed in samples from different wom...

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Detalles Bibliográficos
Autores principales: Hopp, Thomas P., Spiewak, Klaudyna, Matthews, Maura-Ann H., Athanasiou, Zafeiria, Blackmore, Richard S., Gelbfish, Gary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119511/
https://www.ncbi.nlm.nih.gov/pubmed/35587943
http://dx.doi.org/10.1371/journal.pone.0268537