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Characterization of proteolytic degradation products of vaginally administered bovine lactoferrin
When bovine lactoferrin (bLF) contacts human vaginal fluid (VF) it is subjected to proteolytic degradation. This report describes fragmentation patterns of bLF dosed vaginally in clinical trials or incubated ex vivo with VF. A consensus pattern of fragments was observed in samples from different wom...
Autores principales: | Hopp, Thomas P., Spiewak, Klaudyna, Matthews, Maura-Ann H., Athanasiou, Zafeiria, Blackmore, Richard S., Gelbfish, Gary A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119511/ https://www.ncbi.nlm.nih.gov/pubmed/35587943 http://dx.doi.org/10.1371/journal.pone.0268537 |
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