Mice lacking the mitochondrial exonuclease MGME1 develop inflammatory kidney disease with glomerular dysfunction

Mitochondrial DNA (mtDNA) maintenance disorders are caused by mutations in ubiquitously expressed nuclear genes and lead to syndromes with variable disease severity and tissue-specific phenotypes. Loss of function mutations in the gene encoding the mitochondrial genome and maintenance exonuclease 1...

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Detalles Bibliográficos
Autores principales: Milenkovic, Dusanka, Sanz-Moreno, Adrián, Calzada-Wack, Julia, Rathkolb, Birgit, Veronica Amarie, Oana, Gerlini, Raffaele, Aguilar-Pimentel, Antonio, Misic, Jelena, Simard, Marie-Lune, Wolf, Eckhard, Fuchs, Helmut, Gailus-Durner, Valerie, de Angelis, Martin Hrabě, Larsson, Nils-Göran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119528/
https://www.ncbi.nlm.nih.gov/pubmed/35533204
http://dx.doi.org/10.1371/journal.pgen.1010190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119528/
https://www.ncbi.nlm.nih.gov/pubmed/35533204
http://dx.doi.org/10.1371/journal.pgen.1010190

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