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Nano-hydroxyapatite improves intestinal absorption of acetazolamide (BCS Class IV drug)–but how?
We earlier reported that coating poorly water-soluble drugs with nano-hydroxyapatite (nano-HAP) improves bioavailability after oral administration. In the present study, we coated BCS Class IV drug acetazolamide (AZ) with nano-HAP (AZ/HAP formulation), and investigated its bioavailability and nano-H...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119549/ https://www.ncbi.nlm.nih.gov/pubmed/35588130 http://dx.doi.org/10.1371/journal.pone.0268067 |