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The Chemokine (C-C Motif) Receptor 2 Antagonist INCB3284 Reduces Fluid Requirements and Protects From Hemodynamic Decompensation During Resuscitation From Hemorrhagic Shock

Clinical correlations suggest that systemic chemokine (C-C motif) ligand (CCL) 2 release may contribute to blood pressure regulation and the development of hemodynamic instability during the early inflammatory response to traumatic-hemorrhagic shock. Thus, we investigated whether blockade of the pri...

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Detalles Bibliográficos
Autores principales: DeSantis, Anthony J., Weche, McWayne, Enten, Garrett A., Gao, Xianlong, Majetschak, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119637/
https://www.ncbi.nlm.nih.gov/pubmed/35620770
http://dx.doi.org/10.1097/CCE.0000000000000701