TRIM25 and ZAP target the Ebola virus ribonucleoprotein complex to mediate interferon-induced restriction

Ebola virus (EBOV) causes highly pathogenic disease in primates. Through screening a library of human interferon-stimulated genes (ISGs), we identified TRIM25 as a potent inhibitor of EBOV transcription-and-replication-competent virus-like particle (trVLP) propagation. TRIM25 overexpression inhibite...

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Detalles Bibliográficos
Autores principales: Galão, Rui Pedro, Wilson, Harry, Schierhorn, Kristina L., Debeljak, Franka, Bodmer, Bianca S., Goldhill, Daniel, Hoenen, Thomas, Wilson, Sam J., Swanson, Chad M., Neil, Stuart J. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119685/
https://www.ncbi.nlm.nih.gov/pubmed/35533151
http://dx.doi.org/10.1371/journal.ppat.1010530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119685/
https://www.ncbi.nlm.nih.gov/pubmed/35533151
http://dx.doi.org/10.1371/journal.ppat.1010530

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