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TRIM25 and ZAP target the Ebola virus ribonucleoprotein complex to mediate interferon-induced restriction

Ebola virus (EBOV) causes highly pathogenic disease in primates. Through screening a library of human interferon-stimulated genes (ISGs), we identified TRIM25 as a potent inhibitor of EBOV transcription-and-replication-competent virus-like particle (trVLP) propagation. TRIM25 overexpression inhibite...

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Detalles Bibliográficos
Autores principales:	Galão, Rui Pedro, Wilson, Harry, Schierhorn, Kristina L., Debeljak, Franka, Bodmer, Bianca S., Goldhill, Daniel, Hoenen, Thomas, Wilson, Sam J., Swanson, Chad M., Neil, Stuart J. D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119685/ https://www.ncbi.nlm.nih.gov/pubmed/35533151 http://dx.doi.org/10.1371/journal.ppat.1010530

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