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Blockage of Fibronectin 1 Ameliorates Myocardial Ischemia/Reperfusion Injury in Association with Activation of AMP-LKB1-AMPK Signaling Pathway

Myocardial ischemia/reperfusion injury (I/RI) is closely associated with energy substrate metabolism. Fibronectin 1 (Fn1) was markedly elevated in the heart of I/R pigs and ischemic patients, but its role in myocardial I/RI is controversial and the precise mechanism involved remains elusive. Herein,...

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Detalles Bibliográficos
Autores principales: Zhang, Yun-Long, Li, Pang-Bo, Han, Xiao, Zhang, Bo, Li, Hui-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119763/
https://www.ncbi.nlm.nih.gov/pubmed/35602095
http://dx.doi.org/10.1155/2022/6196173