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Impact of proton-pump inhibitors on the efficacy of immune checkpoint inhibitors in non-small cell lung cancer: A systematic review and meta-analysis

INTRODUCTION: Immune checkpoint inhibitors (ICI) is a rapidly evolving treatment modality for stage IV non-small cell lung cancer (NSCLC). Concomitant proton pump inhibitor (PPI) use can potentially reduce the clinical efficacy of ICIs; however, the consensus in recent literature has been conflictin...

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Detalles Bibliográficos
Autores principales: Dar, Sophia, Merza, Nooraldin, Rahim, Mehek, Qatani, Ahmad, Varughese, Tony, Mohammad, Asna, Masood, Fahad, Reza, Fizza, Shucenwan, Almas, Talal, Ellahi, Aayat, Ligresti, Rosario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119820/
https://www.ncbi.nlm.nih.gov/pubmed/35600176
http://dx.doi.org/10.1016/j.amsu.2022.103752