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A bio-functional polymer that prevents retinal scarring through modulation of NRF2 signalling pathway

One common cause of vision loss after retinal detachment surgery is the formation of proliferative and contractile fibrocellular membranes. This aberrant wound healing process is mediated by epithelial-mesenchymal transition (EMT) and hyper-proliferation of retinal pigment epithelial (RPE) cells. Cu...

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Detalles Bibliográficos
Autores principales: Parikh, Bhav Harshad, Liu, Zengping, Blakeley, Paul, Lin, Qianyu, Singh, Malay, Ong, Jun Yi, Ho, Kim Han, Lai, Joel Weijia, Bogireddi, Hanumakumar, Tran, Kim Chi, Lim, Jason Y. C., Xue, Kun, Al-Mubaarak, Abdurrahmaan, Yang, Binxia, R, Sowmiya, Regha, Kakkad, Wong, Daniel Soo Lin, Tan, Queenie Shu Woon, Zhang, Zhongxing, Jeyasekharan, Anand D., Barathi, Veluchamy Amutha, Yu, Weimiao, Cheong, Kang Hao, Blenkinsop, Timothy A., Hunziker, Walter, Lingam, Gopal, Loh, Xian Jun, Su, Xinyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119969/
https://www.ncbi.nlm.nih.gov/pubmed/35589753
http://dx.doi.org/10.1038/s41467-022-30474-6