Palmitoylated prolactin-releasing peptide treatment had neuroprotective but not anti-obesity effect in fa/fa rats with leptin signaling disturbances

BACKGROUND/OBJECTIVE: Anorexigenic palmitoylated prolactin-releasing peptide (palm(11)-PrRP) is able to act centrally after peripheral administration in rat and mouse models of obesity, type 2 diabetes mellitus and/or neurodegeneration. Functional leptin and intact leptin signaling pathways are nece...

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Detalles Bibliográficos
Autores principales: Mráziková, Lucia, Hojná, Silvie, Pačesová, Andrea, Hrubá, Lucie, Strnadová, Veronika, Neprašová, Barbora, Železná, Blanka, Kuneš, Jaroslav, Maletínská, Lenka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119973/
https://www.ncbi.nlm.nih.gov/pubmed/35589696
http://dx.doi.org/10.1038/s41387-022-00205-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119973/
https://www.ncbi.nlm.nih.gov/pubmed/35589696
http://dx.doi.org/10.1038/s41387-022-00205-3

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