Cargando…

Palmitoylated prolactin-releasing peptide treatment had neuroprotective but not anti-obesity effect in fa/fa rats with leptin signaling disturbances

BACKGROUND/OBJECTIVE: Anorexigenic palmitoylated prolactin-releasing peptide (palm(11)-PrRP) is able to act centrally after peripheral administration in rat and mouse models of obesity, type 2 diabetes mellitus and/or neurodegeneration. Functional leptin and intact leptin signaling pathways are nece...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mráziková, Lucia, Hojná, Silvie, Pačesová, Andrea, Hrubá, Lucie, Strnadová, Veronika, Neprašová, Barbora, Železná, Blanka, Kuneš, Jaroslav, Maletínská, Lenka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119973/ https://www.ncbi.nlm.nih.gov/pubmed/35589696 http://dx.doi.org/10.1038/s41387-022-00205-3

Ejemplares similares

Metabolomic Study of Aging in fa/fa Rats: Multiplatform Urine and Serum Analysis
por: Pelantová, Helena, et al.
Publicado: (2023)

Lipidized Prolactin-Releasing Peptide as a New Potential Tool to Treat Obesity and Type 2 Diabetes Mellitus: Preclinical Studies in Rodent Models
por: Mráziková, Lucia, et al.
Publicado: (2021)

Age-related metabolic and neurodegenerative changes in SAMP8 mice
por: Pačesová, Andrea, et al.
Publicado: (2022)

Palmitoylation of Prolactin-Releasing Peptide Increased Affinity for and Activation of the GPR10, NPFF-R2 and NPFF-R1 Receptors: In Vitro Study
por: Karnošová, Alena, et al.
Publicado: (2021)

Lipidized PrRP Analog Exhibits Strong Anti-Obesity and Antidiabetic Properties in Old WKY Rats with Obesity and Glucose Intolerance
por: Mráziková, Lucia, et al.
Publicado: (2023)

Lipidized prolactin-releasing peptide improved glucose tolerance in metabolic syndrome: Koletsky and spontaneously hypertensive rat study
por: Mikulášková, Barbora, et al.
Publicado: (2018)

Impact of novel palmitoylated prolactin-releasing peptide analogs on metabolic changes in mice with diet-induced obesity
por: Pražienková, Veronika, et al.
Publicado: (2017)

Cellular Signaling and Anti-Apoptotic Effects of Prolactin-Releasing Peptide and Its Analog on SH-SY5Y Cells
por: Zmeškalová, Anna, et al.
Publicado: (2020)

NPFFR2-deficient mice fed a high-fat diet develop strong intolerance to glucose
por: Karnošová, Alena, et al.
Publicado: (2023)

Feeding High-Fat Diet Accelerates Development of Peripheral and Central Insulin Resistance and Inflammation and Worsens AD-like Pathology in APP/PS1 Mice
por: Mengr, Anna, et al.
Publicado: (2023)

Prolactin-Releasing Peptide: Physiological and Pharmacological Properties
por: Pražienková, Veronika, et al.
Publicado: (2019)

Aging and high-fat diet feeding lead to peripheral insulin resistance and sex-dependent changes in brain of mouse model of tau pathology THY-Tau22
por: Kacířová, Miroslava, et al.
Publicado: (2021)

Obesity and Age-Related Changes in the Brain of the Zucker Lepr (fa/fa) Rats
por: Tomassoni, Daniele, et al.
Publicado: (2020)

A never-ending story: the steadily growing family of the FA and FA-like genes
por: Gueiderikh, Anna, et al.
Publicado: (2017)

DGAT inhibition at the post‐absorptive phase reduces plasma FA by increasing FA oxidation
por: Sharma, Anand Kumar, et al.
Publicado: (2023)

FaGAPC2/FaPKc2.2 and FaPEPCK reveal differential citric acid metabolism regulation in late development of strawberry fruit
por: Yang, Min, et al.
Publicado: (2023)

The blue light signal transduction module FaCRY1-FaCOP1-FaHY5 regulates anthocyanin accumulation in cultivated strawberry
por: Liu, Yongqiang, et al.
Publicado: (2023)

Son en fa menor
por: García Caturla, Alejandro, 1906-1940
Publicado: (1975)

Il Cern fa sboom
Publicado: (2009)

FÄ: Corona entzaubert Telemedizin
por: Hardt, Wolfgang
Publicado: (2020)

Excessive Food Intake, Obesity and Inflammation Process in Zucker fa/fa Rat Pancreatic Islets
por: Chentouf, Myriam, et al.
Publicado: (2011)

Immuno-Modulator Metallo-Peptide Reduces Inflammatory State in Obese Zucker Fa/Fa Rats
por: Gómez-Solís, Antonieta, et al.
Publicado: (2014)

Diabetes-associated microbiota in fa/fa rats is modified by Roux-en-Y gastric bypass
por: Arora, Tulika, et al.
Publicado: (2017)

Pathophysiology of NAFLD and NASH in Experimental Models: The Role of Food Intake Regulating Peptides
por: Kořínková, L., et al.
Publicado: (2020)

Na,K-ATPase Kinetics and Oxidative Stress in Kidneys of Zucker Diabetic Fatty (fa/fa) Rats Depending on the Diabetes Severity—Comparison with Lean (fa/+) and Wistar Rats
por: Vrbjar, Norbert, et al.
Publicado: (2022)

Remarkable features of ovarian morphology and reproductive hormones in insulin-resistant Zucker fatty (fa/fa) rats
por: Honnma, Hiroyuki, et al.
Publicado: (2010)

Ier concerto Brandebourgeois : Fa mayor : Fa mayor : F Dur P. H. I9/

Pioglitazone is effective for multiple phenotyepes of the Zucker fa/fa rat with polycystc ovary morphology and insulin resistance
por: Morishita, Miyuki, et al.
Publicado: (2018)

Concerto fa maggiore per due fagotti ed orchestra ; Sinfonia in fa maggiore ; Sinfonia in la minore
por: Vanhal, Johann Baptist, 1739-1813
Publicado: (1985)

Red Wine Polyphenols Prevent Metabolic and Cardiovascular Alterations Associated with Obesity in Zucker Fatty Rats (Fa/Fa)
por: Agouni, Abdelali, et al.
Publicado: (2009)

Characterization of a new animal model of metabolic syndrome: the DahlS.Z-Lepr(fa)/Lepr(fa) rat
por: Hattori, T, et al.
Publicado: (2011)

Restoration of Euglycemia After Duodenal Bypass Surgery Is Reliant on Central and Peripheral Inputs in Zucker fa/fa Rats
por: Jiao, Jian, et al.
Publicado: (2013)

Ligand Binding to the FA3-FA4 Cleft Inhibits the Esterase-Like Activity of Human Serum Albumin
por: Ascenzi, Paolo, et al.
Publicado: (2015)

FXR-mediated inhibition of autophagy contributes to FA-induced TG accumulation and accordingly reduces FA-induced lipotoxicity
por: Wu, Kun, et al.
Publicado: (2020)

FaMYB5 Interacts with FaBBX24 to Regulate Anthocyanin and Proanthocyanidin Biosynthesis in Strawberry (Fragaria × ananassa)
por: Zhang, Lianxi, et al.
Publicado: (2023)

Concerto in Fa maggiore : Per 2 corni, archi e cembalo /
por: Vivaldi, Antonio

Kodamaeahongheensis f.a., sp. nov., Kodamaeaovata f.a., sp. nov. and Kodamaeayamadae f.a., sp. nov., three new yeast species of Kodamaea (Saccharomycetales, Debaryomycetacae) from China
por: Chai, Chun-Yue, et al.
Publicado: (2022)

Effects of baked and raw salmon fillet on lipids and n-3 PUFAs in serum and tissues in Zucker fa/fa rats
por: Vikøren, Linn A., et al.
Publicado: (2017)

Role of FaSOC1 and FaCO in the seasonal control of reproductive and vegetative development in the perennial crop Fragaria × ananassa
por: Muñoz-Avila, Julio C., et al.
Publicado: (2022)

Do, Re, Mi, Fa, Vals fácil
por: Streabbog, Louis, 1835-1886

Cannot write session to /tmp/vufind_sessions/sess_ttfeors6bshm547ibg0s841vm1