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Conformational spread drives the evolution of the calcium–calmodulin protein kinase II
The calcium calmodulin (Ca(2+)/CaM) dependent protein kinase II (CaMKII) decodes Ca(2+) frequency oscillations. The CaMKIIα isoform is predominantly expressed in the brain and has a central role in learning. I matched residue and organismal evolution with collective motions deduced from the atomic s...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120016/ https://www.ncbi.nlm.nih.gov/pubmed/35589775 http://dx.doi.org/10.1038/s41598-022-12090-y |