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circ-Pank1 promotes dopaminergic neuron neurodegeneration through modulating miR-7a-5p/α-syn pathway in Parkinson’s disease

Circular RNA (circRNA) is a type of non-coding RNA that is widely expressed in mammals. It is highly conserved and abundantly expressed in the brain. Here, we report the regulatory role of circRNA derived from the pantothenate kinase 1 (Pank1) gene (circ-Pank1) in Parkinson’s disease (PD). Circ-Pank...

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Detalles Bibliográficos
Autores principales: Liu, Qing, Li, Qiyao, Zhang, Runjiao, Wang, Hongfang, Li, Yibo, Liu, Ziyu, Xie, Wenmeng, Geng, Dandan, Wang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120029/
https://www.ncbi.nlm.nih.gov/pubmed/35589691
http://dx.doi.org/10.1038/s41419-022-04934-2