SARS-CoV-2 ORF6 disrupts nucleocytoplasmic trafficking to advance viral replication

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ORF6 is an antagonist of interferon (IFN)-mediated antiviral signaling, achieved through the prevention of STAT1 nuclear localization. However, the exact mechanism through which ORF6 prevents STAT1 nuclear trafficking remains unclear. Here...

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Detalles Bibliográficos
Autores principales: Miyamoto, Yoichi, Itoh, Yumi, Suzuki, Tatsuya, Tanaka, Tomohisa, Sakai, Yusuke, Koido, Masaru, Hata, Chiaki, Wang, Cai-Xia, Otani, Mayumi, Moriishi, Kohji, Tachibana, Taro, Kamatani, Yoichiro, Yoneda, Yoshihiro, Okamoto, Toru, Oka, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120032/
https://www.ncbi.nlm.nih.gov/pubmed/35590097
http://dx.doi.org/10.1038/s42003-022-03427-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120032/
https://www.ncbi.nlm.nih.gov/pubmed/35590097
http://dx.doi.org/10.1038/s42003-022-03427-4

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