SARS-CoV-2 infection results in immune responses in the respiratory tract and peripheral blood that suggest mechanisms of disease severity

Respiratory tract infection with SARS-CoV-2 results in varying immunopathology underlying COVID-19. We examine cellular, humoral and cytokine responses covering 382 immune components in longitudinal blood and respiratory samples from hospitalized COVID-19 patients. SARS-CoV-2-specific IgM, IgG, IgA...

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Detalles Bibliográficos
Autores principales: Zhang, Wuji, Chua, Brendon Y., Selva, Kevin J., Kedzierski, Lukasz, Ashhurst, Thomas M., Haycroft, Ebene R., Shoffner-Beck, Suzanne K., Hensen, Luca, Boyd, David F., James, Fiona, Mouhtouris, Effie, Kwong, Jason C., Chua, Kyra Y. L., Drewett, George, Copaescu, Ana, Dobson, Julie E., Rowntree, Louise C., Habel, Jennifer R., Allen, Lilith F., Koay, Hui-Fern, Neil, Jessica A., Gartner, Matthew J., Lee, Christina Y., Andersson, Patiyan, Khan, Sadid F., Blakeway, Luke, Wisniewski, Jessica, McMahon, James H., Vine, Erica E., Cunningham, Anthony L., Audsley, Jennifer, Thevarajan, Irani, Seemann, Torsten, Sherry, Norelle L., Amanat, Fatima, Krammer, Florian, Londrigan, Sarah L., Wakim, Linda M., King, Nicholas J. C., Godfrey, Dale I., Mackay, Laura K., Thomas, Paul G., Nicholson, Suellen, Arnold, Kelly B., Chung, Amy W., Holmes, Natasha E., Smibert, Olivia C., Trubiano, Jason A., Gordon, Claire L., Nguyen, Thi H. O., Kedzierska, Katherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120039/
https://www.ncbi.nlm.nih.gov/pubmed/35589689
http://dx.doi.org/10.1038/s41467-022-30088-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120039/
https://www.ncbi.nlm.nih.gov/pubmed/35589689
http://dx.doi.org/10.1038/s41467-022-30088-y

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