Mitochondrial calcium uniporter stabilization preserves energetic homeostasis during Complex I impairment

Calcium entering mitochondria potently stimulates ATP synthesis. Increases in calcium preserve energy synthesis in cardiomyopathies caused by mitochondrial dysfunction, and occur due to enhanced activity of the mitochondrial calcium uniporter channel. The signaling mechanism that mediates this compe...

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Detalles Bibliográficos
Autores principales: Balderas, Enrique, Eberhardt, David R., Lee, Sandra, Pleinis, John M., Sommakia, Salah, Balynas, Anthony M., Yin, Xue, Parker, Mitchell C., Maguire, Colin T., Cho, Scott, Szulik, Marta W., Bakhtina, Anna, Bia, Ryan D., Friederich, Marisa W., Locke, Timothy M., Van Hove, Johan L. K., Drakos, Stavros G., Sancak, Yasemin, Tristani-Firouzi, Martin, Franklin, Sarah, Rodan, Aylin R., Chaudhuri, Dipayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120069/
https://www.ncbi.nlm.nih.gov/pubmed/35589699
http://dx.doi.org/10.1038/s41467-022-30236-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120069/
https://www.ncbi.nlm.nih.gov/pubmed/35589699
http://dx.doi.org/10.1038/s41467-022-30236-4

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