Genome-wide association of polygenic risk extremes for Alzheimer's disease in the UK Biobank

In just over a decade, advances in genome-wide association studies (GWAS) have offered an approach to stratify individuals based on genetic risk for disease. Using recent Alzheimer's disease (AD) GWAS results as the base data, we determined each individual's polygenic risk score (PRS) in t...

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Detalles Bibliográficos
Autores principales: Gouveia, Catarina, Gibbons, Elizabeth, Dehghani, Nadia, Eapen, James, Guerreiro, Rita, Bras, Jose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120074/
https://www.ncbi.nlm.nih.gov/pubmed/35589863
http://dx.doi.org/10.1038/s41598-022-12391-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120074/
https://www.ncbi.nlm.nih.gov/pubmed/35589863
http://dx.doi.org/10.1038/s41598-022-12391-2

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