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RNP components condense into repressive RNP granules in the aging brain

Cytoplasmic RNP condensates enriched in mRNAs and proteins are found in various cell types and associated with both buffering and regulatory functions. While a clear link has been established between accumulation of aberrant RNP aggregates and progression of aging-related neurodegenerative diseases,...

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Detalles Bibliográficos
Autores principales: Pushpalatha, Kavya Vinayan, Solyga, Mathilde, Nakamura, Akira, Besse, Florence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120078/
https://www.ncbi.nlm.nih.gov/pubmed/35589695
http://dx.doi.org/10.1038/s41467-022-30066-4