Fgfr2b signaling is essential for the maintenance of the alveolar epithelial type 2 lineage during lung homeostasis in mice

Fibroblast growth factor receptor 2b (Fgfr2b) signaling is essential throughout lung development to form the alveolar epithelial lineage. However, its role in alveolar epithelial type 2 cells (AT2s) homeostasis was recently considered dispensable. Sftpc(CreERT2); Fgfr2b(flox/flox); tdTomato(flox/flo...

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Autores principales: Ahmadvand, Negah, Lingampally, Arun, Khosravi, Farhad, Vazquez-Armendariz, Ana Ivonne, Rivetti, Stefano, Jones, Matthew R., Wilhelm, Jochen, Herold, Susanne, Barreto, Guillermo, Koepke, Janine, Samakovlis, Christos, Carraro, Gianni, Zhang, Jin-San, Al Alam, Denise, Bellusci, Saverio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120111/
https://www.ncbi.nlm.nih.gov/pubmed/35587837
http://dx.doi.org/10.1007/s00018-022-04327-w