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A truncated anti-CRISPR protein prevents spacer acquisition but not interference

CRISPR-Cas systems in prokaryotic cells provide an adaptive immunity against invading nucleic acids. For example, phage infection leads to addition of new immunity (spacer acquisition) and DNA cleavage (interference) in the bacterial model species Streptococcus thermophilus, which primarily relies o...

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Detalles Bibliográficos
Autores principales: Philippe, Cécile, Morency, Carlee, Plante, Pier-Luc, Zufferey, Edwige, Achigar, Rodrigo, Tremblay, Denise M., Rousseau, Geneviève M., Goulet, Adeline, Moineau, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120153/
https://www.ncbi.nlm.nih.gov/pubmed/35589712
http://dx.doi.org/10.1038/s41467-022-30310-x