IL-33 enhances Jagged1 mediated NOTCH1 intracellular domain (NICD) deubiquitination and pathological angiogenesis in proliferative retinopathy

Pathological retinal neovascularization (NV) is a clinical manifestation of various proliferative retinopathies, and treatment of NV using anti-VEGF therapies is not selective, as it also impairs normal retinal vascular growth and function. Here, we show that genetic deletion or siRNA-mediated downr...

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Detalles Bibliográficos
Autores principales: Sharma, Deepti, Bisen, Shivantika, Kaur, Geetika, Van Buren, Eric C., Rao, Gadiparthi N., Singh, Nikhlesh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120174/
https://www.ncbi.nlm.nih.gov/pubmed/35589941
http://dx.doi.org/10.1038/s42003-022-03432-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120174/
https://www.ncbi.nlm.nih.gov/pubmed/35589941
http://dx.doi.org/10.1038/s42003-022-03432-7

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