Identification of adeno-associated virus variants for gene transfer into human neural cell types by parallel capsid screening

Human brain cells generated by in vitro cell programming provide exciting prospects for disease modeling, drug discovery and cell therapy. These applications frequently require efficient and clinically compliant tools for genetic modification of the cells. Recombinant adeno-associated viruses (AAVs)...

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Detalles Bibliográficos
Autores principales: Flitsch, Lea Jessica, Börner, Kathleen, Stüllein, Christian, Ziegler, Simon, Sonntag-Buck, Vera, Wiedtke, Ellen, Semkova, Vesselina, Au Yeung, Si Wah Christina, Schlee, Julia, Hajo, Mohamad, Mathews, Mona, Ludwig, Beatrice Stefanie, Kossatz, Susanne, Kessler, Horst, Grimm, Dirk, Brüstle, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120183/
https://www.ncbi.nlm.nih.gov/pubmed/35589936
http://dx.doi.org/10.1038/s41598-022-12404-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120183/
https://www.ncbi.nlm.nih.gov/pubmed/35589936
http://dx.doi.org/10.1038/s41598-022-12404-0

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