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Cytosolic peptides encoding Ca(V)1 C-termini downregulate the calcium channel activity-neuritogenesis coupling

L-type Ca(2+) (Ca(V)1) channels transduce channel activities into nuclear signals critical to neuritogenesis. Also, standalone peptides encoded by Ca(V)1 DCT (distal carboxyl-terminus) act as nuclear transcription factors reportedly promoting neuritogenesis. Here, by focusing on exemplary Ca(V)1.3 a...

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Detalles Bibliográficos
Autores principales: Yang, Yaxiong, Yu, Zhen, Geng, Jinli, Liu, Min, Liu, Nan, Li, Ping, Hong, Weili, Yue, Shuhua, Jiang, He, Ge, Haiyan, Qian, Feng, Xiong, Wei, Wang, Ping, Song, Sen, Li, Xiaomei, Fan, Yubo, Liu, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120191/
https://www.ncbi.nlm.nih.gov/pubmed/35589958
http://dx.doi.org/10.1038/s42003-022-03438-1