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Templated folding of the RTX domain of the bacterial toxin adenylate cyclase revealed by single molecule force spectroscopy
The RTX (repeats-in-toxin) domain of the bacterial toxin adenylate cyclase (CyaA) contains five RTX blocks (RTX-i to RTX-v) and its folding is essential for CyaA’s functions. It was shown that the C-terminal capping structure of RTX-v is critical for the whole RTX to fold. However, it is unknown how...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120197/ https://www.ncbi.nlm.nih.gov/pubmed/35589788 http://dx.doi.org/10.1038/s41467-022-30448-8 |