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Free fatty acid receptor 4 deletion attenuates colitis by modulating Treg Cells via ZBED6-IL33 pathway

BACKGROUND: Inflammatory bowel disease (IBD) has complex genetic and environmental aspects, and free fatty acid receptors (FFARs) may bridge genetic and dietary aspects. FFAR4 is highly expressed in the intestine and acts primarily as the receptor of long-chain fatty acids, which are major component...

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Detalles Bibliográficos
Autores principales: Zhu, Shenglong, Zhang, Jingwei, Jiang, Xuan, Wang, Wei, Chen, Yong Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120243/
https://www.ncbi.nlm.nih.gov/pubmed/35588628
http://dx.doi.org/10.1016/j.ebiom.2022.104060