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Survival of Stem Cells and Progenitors in the Intestine Is Regulated by LPA(5)-Dependent Signaling

BACKGROUND & AIMS: Regeneration of the epithelium by stem cells in the intestine is supported by intrinsic and extrinsic factors. Lysophosphatidic acid (LPA), a bioactive lipid mediator, regulates many cellular functions, including cell proliferation, survival, and cytokine secretion. Here, we i...

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Detalles Bibliográficos
Autores principales: Liang, Zhongxing, He, Peijian, Han, Yiran, Yun, C. Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120264/
https://www.ncbi.nlm.nih.gov/pubmed/35390517
http://dx.doi.org/10.1016/j.jcmgh.2022.03.012