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Annexin-A1 Tripeptide Attenuates Surgery-Induced Neuroinflammation and Memory Deficits Through Regulation the NLRP3 Inflammasome

Neuroinflammation is a growing hallmark of perioperative neurocognitive disorders (PNDs), including delirium and longer-lasting cognitive deficits. We have developed a clinically relevant orthopedic mouse model to study the impact of a common surgical procedure on the vulnerable brain. The mechanism...

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Detalles Bibliográficos
Autores principales: Zhang, Zhiquan, Ma, Qing, Velagapudi, Ravikanth, Barclay, William E., Rodriguiz, Ramona M., Wetsel, William C., Yang, Ting, Shinohara, Mari L., Terrando, Niccolò
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120413/
https://www.ncbi.nlm.nih.gov/pubmed/35603196
http://dx.doi.org/10.3389/fimmu.2022.856254