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Annexin-A1 Tripeptide Attenuates Surgery-Induced Neuroinflammation and Memory Deficits Through Regulation the NLRP3 Inflammasome
Neuroinflammation is a growing hallmark of perioperative neurocognitive disorders (PNDs), including delirium and longer-lasting cognitive deficits. We have developed a clinically relevant orthopedic mouse model to study the impact of a common surgical procedure on the vulnerable brain. The mechanism...
Autores principales: | Zhang, Zhiquan, Ma, Qing, Velagapudi, Ravikanth, Barclay, William E., Rodriguiz, Ramona M., Wetsel, William C., Yang, Ting, Shinohara, Mari L., Terrando, Niccolò |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120413/ https://www.ncbi.nlm.nih.gov/pubmed/35603196 http://dx.doi.org/10.3389/fimmu.2022.856254 |
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