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Exogenous loading of extracellular vesicles, virus-like particles, and lentiviral vectors with supercharged proteins

Cell membrane-based biovesicles (BVs) are important candidate drug delivery vehicles and comprise extracellular vesicles, virus-like particles, and lentiviral vectors. Here, we introduce a non-enzymatic assembly of purified BVs, supercharged proteins, and plasmid DNA called pDNA-scBVs. This multicom...

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Detalles Bibliográficos
Autores principales: Breyne, Koen, Ughetto, Stefano, Rufino-Ramos, David, Mahjoum, Shadi, Grandell, Emily A., de Almeida, Luís P., Breakefield, Xandra O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120435/
https://www.ncbi.nlm.nih.gov/pubmed/35590035
http://dx.doi.org/10.1038/s42003-022-03440-7