BMP4 drives primed to naïve transition through PGC-like state

Multiple pluripotent states have been described in mouse and human stem cells. Here, we apply single-cell RNA-seq to a newly established BMP4 induced mouse primed to naïve transition (BiPNT) system and show that the reset is not a direct reversal of cell fate but goes through a primordial germ cell-...

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Detalles Bibliográficos
Autores principales: Yu, Shengyong, Zhou, Chunhua, He, Jiangping, Yao, Zhaokai, Huang, Xingnan, Rong, Bowen, Zhu, Hong, Wang, Shijie, Chen, Shuyan, Wang, Xialian, Cai, Baomei, Zhao, Guoqing, Chen, Yuhan, Xiao, Lizhan, Liu, He, Qin, Yue, Guo, Jing, Wu, Haokaifeng, Zhang, Zhen, Zhang, Man, Zhao, Xiaoyang, Lan, Fei, Wang, Yixuan, Chen, Jiekai, Cao, Shangtao, Pei, Duanqing, Liu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120449/
https://www.ncbi.nlm.nih.gov/pubmed/35589713
http://dx.doi.org/10.1038/s41467-022-30325-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120449/
https://www.ncbi.nlm.nih.gov/pubmed/35589713
http://dx.doi.org/10.1038/s41467-022-30325-4

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