Cargando…

Shielding of actin by the endoplasmic reticulum impacts nuclear positioning

Nuclear position is central to cell polarization, and its disruption is associated with various pathologies. The nucleus is moved away from the leading edge of migrating cells through its connection to moving dorsal actin cables, and the absence of connections to immobile ventral stress fibers. It i...

Descripción completa

Detalles Bibliográficos
Autores principales: Janota, Cátia Silva, Pinto, Andreia, Pezzarossa, Anna, Machado, Pedro, Costa, Judite, Campinho, Pedro, Franco, Cláudio A., Gomes, Edgar R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120458/
https://www.ncbi.nlm.nih.gov/pubmed/35589708
http://dx.doi.org/10.1038/s41467-022-30388-3