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Shielding of actin by the endoplasmic reticulum impacts nuclear positioning
Nuclear position is central to cell polarization, and its disruption is associated with various pathologies. The nucleus is moved away from the leading edge of migrating cells through its connection to moving dorsal actin cables, and the absence of connections to immobile ventral stress fibers. It i...
Autores principales: | Janota, Cátia Silva, Pinto, Andreia, Pezzarossa, Anna, Machado, Pedro, Costa, Judite, Campinho, Pedro, Franco, Cláudio A., Gomes, Edgar R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120458/ https://www.ncbi.nlm.nih.gov/pubmed/35589708 http://dx.doi.org/10.1038/s41467-022-30388-3 |
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