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Structural mechanism of TRPV3 channel inhibition by the anesthetic dyclonine
Skin diseases are common human illnesses that occur in all cultures, at all ages, and affect between 30% and 70% of individuals globally. TRPV3 is a cation-permeable TRP channel predominantly expressed in skin keratinocytes, implicated in cutaneous sensation and associated with numerous skin disease...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120478/ https://www.ncbi.nlm.nih.gov/pubmed/35589741 http://dx.doi.org/10.1038/s41467-022-30537-8 |