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Modeling pulsativity in the hypothalamic–pituitary–adrenal hormonal axis

A new mathematical model for biological rhythms in the hypothalamic–pituitary–adrenal (HPA) axis is proposed. This model takes the form of a system of impulsive time-delay differential equations which include pulsatile release of adrenocorticotropin (ACTH) by the pituitary gland and a time delay for...

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Detalles Bibliográficos
Autores principales: Churilov, Alexander N., Milton, John G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120490/
https://www.ncbi.nlm.nih.gov/pubmed/35589935
http://dx.doi.org/10.1038/s41598-022-12513-w