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Histone macroH2A1 is a stronger regulator of hippocampal transcription and memory than macroH2A2 in mice

Histone variants H2A.Z and H3.3 are epigenetic regulators of memory, but roles of other variants are not well characterized. macroH2A (mH2A) is a structurally unique histone that contains a globular macrodomain connected to the histone region by an unstructured linker. Here we assessed if mH2A regul...

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Detalles Bibliográficos
Autores principales: Singh, Gurdeep, Stefanelli, Gilda, Narkaj, Klotilda, Brimble, Mark A., Creighton, Samantha D., McLean, Timothy A. B., Hall, Meaghan, Mitchnick, Krista A., Zakaria, Jacqueline, Phung, Thanh, Reda, Anas, Leonetti, Amanda M., Monks, Ashley, Ianov, Lara, Winters, Boyer D., Walters, Brandon J., Davidoff, Andrew M., Mitchell, Jennifer A., Zovkic, Iva B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120515/
https://www.ncbi.nlm.nih.gov/pubmed/35590030
http://dx.doi.org/10.1038/s42003-022-03435-4