Systemically Silencing Long Non-coding RNAs Maclpil With Short Interfering RNA Nanoparticles Alleviates Experimental Ischemic Stroke by Promoting Macrophage Apoptosis and Anti-inflammatory Activation

BACKGROUND: Maclpil is a proinflammatory long non-coding RNA highly expressed on monocyte-derived macrophages in the ischemic brain. This study investigated the impact and the mechanisms of systemically delivering nanoparticle Maclpil short interfering RNA (siRNA) on experimental ischemic stroke in...

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Detalles Bibliográficos
Autores principales: Wang, Yan, Liu, Cuiying, Chen, Yong, Chen, Tiffany, Han, Tao, Xue, Lixiang, Xu, Baohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120540/
https://www.ncbi.nlm.nih.gov/pubmed/35600488
http://dx.doi.org/10.3389/fcvm.2022.876087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120540/
https://www.ncbi.nlm.nih.gov/pubmed/35600488
http://dx.doi.org/10.3389/fcvm.2022.876087

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