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Systemically Silencing Long Non-coding RNAs Maclpil With Short Interfering RNA Nanoparticles Alleviates Experimental Ischemic Stroke by Promoting Macrophage Apoptosis and Anti-inflammatory Activation

BACKGROUND: Maclpil is a proinflammatory long non-coding RNA highly expressed on monocyte-derived macrophages in the ischemic brain. This study investigated the impact and the mechanisms of systemically delivering nanoparticle Maclpil short interfering RNA (siRNA) on experimental ischemic stroke in...

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Detalles Bibliográficos
Autores principales:	Wang, Yan, Liu, Cuiying, Chen, Yong, Chen, Tiffany, Han, Tao, Xue, Lixiang, Xu, Baohui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120540/ https://www.ncbi.nlm.nih.gov/pubmed/35600488 http://dx.doi.org/10.3389/fcvm.2022.876087

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