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Patients With Myeloproliferative Neoplasms Harbor High Frequencies of CD8 T Cell-Platelet Aggregates Associated With T Cell Suppression

Myeloproliferative neoplasms (MPN) are chronic cancers of the hematopoietic stem cells in the bone marrow, and patients often harbor elevated numbers of circulating platelets (PLT). We investigated the frequencies of circulating PLT-lymphocyte aggregates in MPN patients and the effect of PLT-binding...

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Detalles Bibliográficos
Autores principales: Carnaz Simões, Ana Micaela, Holmström, Morten Orebo, Aehnlich, Pia, Rahbech, Anne, Peeters, Marlies J. W., Radziwon-Balicka, Aneta, Zamora, Carlos, Wirenfeldt Klausen, Tobias, Skov, Vibe, Kjær, Lasse, Ellervik, Christina, Fassi, Daniel El, Vidal, Silvia, Hasselbalch, Hans Carl, Andersen, Mads Hald, thor Straten, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120544/
https://www.ncbi.nlm.nih.gov/pubmed/35603202
http://dx.doi.org/10.3389/fimmu.2022.866610