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Ginsenoside Rb1 attenuates methamphetamine (METH)-induced neurotoxicity through the NR2B/ERK/CREB/BDNF signalings in vitro and in vivo models

AIM: This study investigates the effects of ginsenoside Rb1 (GsRb1) on methamphetamine (METH)-induced toxicity in SH-SY5Y neuroblastoma cells and METH-induced conditioned place preference (CPP) in adult Sprague-Dawley rats. It also examines whether GsRb1 can regulate these effects through the NR2B/E...

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Detalles Bibliográficos
Autores principales: Yang, Genmeng, Li, Juan, Peng, Yanxia, Shen, Baoyu, Li, Yuanyuan, Liu, Liu, Wang, Chan, Xu, Yue, Lin, Shucheng, Zhang, Shuwei, Tan, Yi, Zhang, Huijie, Zeng, Xiaofeng, Li, Qi, Lu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120644/
https://www.ncbi.nlm.nih.gov/pubmed/35600772
http://dx.doi.org/10.1016/j.jgr.2021.07.005