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Ginsenoside compound K ameliorates palmitate-induced atrophy in C2C12 myotubes via promyogenic effects and AMPK/autophagy-mediated suppression of endoplasmic reticulum stress

BACKGROUND: Compound K (CK) is among the protopanaxadiol (PPD)-type ginsenoside group, which produces multiple pharmacological effects. Herein, we examined the effects of CK on muscle atrophy under hyperlipidemic conditions along with its pro-myogenic effects. Further, the molecular pathways underly...

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Detalles Bibliográficos
Autores principales: Kim, Tae Jin, Pyun, Do Hyeon, Kim, Myeong Jun, Jeong, Ji Hoon, Abd El-Aty, A.M., Jung, Tae Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120645/
https://www.ncbi.nlm.nih.gov/pubmed/35600773
http://dx.doi.org/10.1016/j.jgr.2021.09.002