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Contribution of Amygdala Histone Acetylation in Early Life Stress-Induced Visceral Hypersensitivity and Emotional Comorbidity

Patients with irritable bowel syndrome (IBS) experience not only enhanced visceral pain but also emotional comorbidities, such as anxiety and depression. Early life stress (ELS) is a high-risk for the development of IBS. Literatures have reported an important epigenetic modulation in sustaining extr...

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Detalles Bibliográficos
Autores principales: Guan, Le, Shi, Xi, Tang, Ying, Yan, Yan, Chen, Liang, Chen, Yu, Gao, Guangcheng, Lin, Chun, Chen, Aiqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120649/
https://www.ncbi.nlm.nih.gov/pubmed/35600618
http://dx.doi.org/10.3389/fnins.2022.843396